Forums › Drugs › Amphetamines › dexedrine and potentiation
Hi, I am one of those very lucky people who has add and hence a prescription for 20 mg of Dexedrine every day. My add symptoms, as I have limbic add, a rare form that causes childhood depression and instead of not being able to concentrate I hyperfocus on things I enjoy doing and ignore what I don’t want to do. I’m a programmer and I love it so I can work without daily doses of my favourite drug.
Every week I was taking a week’s worth of Dexedrine, 28 x 5 mg pills and it works great. I have been looking for ways to stretch my usage further and came across DMSO (DiMethylSulfOxide), a solvent, non toxic which is used in veterinary medicine as a horse liniment and can easily be ordered. It has 3 interesting properties first it changes the ibutenic acid in amanita muscaria into the psychoactive ingredient muscimol, second when rubbed on sore muscles it is probably the best painkiller that doesn’t contain morphine, and third anything you mix with it gets absorbed by your skin so you don’t want to have handcream on when you apply it to a sore back.
So, I just decided to experiment, I crushed a half dozen 5 mg tabs in a mortar and pestle and added 5 ml DMSO. As a solvent it dissolved dye, filler, and the Dexedrine and I applied it to my skin and also happened to take 1000 mg of Piracetan, a nootropic that potentiates Dexedrine a wee bit also. The effect was just like my taking the whole 28 tabs even though I’ve already been up 48 hours since taking Dexedrine yesterday. Everything, mood, energy etc. is right on track. The DMSO bottle said causes skin irritation but the itchieness quickly subsided and the effect on the skin is way less than the itch from Heet Lineament.
My next experiment is taking a very very tiny dose of Syrian Rue with a very very tiny dose of Dexedrine, the two together interact excessively, even a half dose of each is a severe health risk, to see if the combination is Dexedrinelike or seriously unpleasant, I’ll start with 1 gram of Syrian Rue and 5 mg of Dexedrine, my heart and blood pressure are good so that I can weather any hypertensive crisis, Syrian Rue contains Harmaline which is an MAOI (Mono Amine Oxidase Inhibitor) which prevents the brain from performing its serotonin and dopamine reuptake and Dexedrine causes extra dopamine to be released into the brain, if both are at full strength the result could be fatal. MAOI’s also interact with most serotonin boosting medication like Zyprexa, Wellbutrin, or Effexor and with foods that contain chemicals like Tryptophan, things like tuna and aged cheese can cause a hypertensive reaction. Never, ever, start using a drug without researching the side-effects, interactions, and the effect on body and brain chemistry. If more people did that we might still be going to see Jimmy Hendrix in concert.
True, substances capable of dissolving in DMSO could be absorbed through skin, but that also goes for any contaminants or things your skin protects you from. Also, it’s recognized as a developmental neurotoxin, so prolonged exposure is probably not the best idea. And one of it’s metabolites (don’t know which one) isn’t a fun thing to have in you. Read up before you lather up, saying it’s not toxic is plain false.. Look up baking soda + amphetamines..
my exposure to DMSO is for athletics they’d give it to runners who were too hurt to compete and then they’d go out and bust ass and do well but then be permanently injured… this has nothing to do with what you’re talking about but RaD brought up some good points.
Also this might interest you-
[URL=”http://http://news.harvard.edu/gazette/story/2014/02/toxic-chemicals-linked-to-brain-disorders-in-children/”%5D’Toxic chemicals linked to brain disorders in children. […] • Solvents are linked to hyperactivity and aggressive behavior.'[/URL]
I don’t know if this applies to DMSO or you, but still, interesting article.
I’ll be honest, it was a TL;DR for me. I’ll try sort that tomorrow :head_bang
Hi, thank you for the heads up on possible DMSO toxicity. I hadn’t looked at what it breaks down into once it enters my metabolism. Actually on a subjective comparison there isn’t an advantage to using DMSO with the amphetamines. I will check out baking soda and amphetamines, the idea intrigues me. I get some small benefits from Piracetan, some herbal l-dopa, a big dose of vitamin b6 and a spoonful of tyrosine seem to get the dopamine flowing more freely.
Yes, I’ll reserve my remaining DMSO to be a catalyst for amanita and and helping when my back gets bad. I overstrained it years ago when I was working in a chemical warehouse. A couple of times a 500 pound barrel was falling over by instinct I grabbed it out of instinct that makes one want to stop falling things and of course gravity and weight won out and I got a nasty wrench of the spine since I’m not even faintly related to superman.
Sorry but couldn’t be arsed reading the whole thread so I am be repeating but my ultimate combo when I was prescribed dexies was one sachet of Ural 15-25 mins before dropping and them 300mg of moclobemide……..guaranteed to be charged for a very longtime on very little
0
Voices
6
Replies
Tags
This topic has no tags
Forums › Drugs › Amphetamines › dexedrine and potentiation