@Barksdale 383495 wrote:
Another ketamine (+ alcohol)story
Alcohol proven lethal catalyst for ketamine users
Its from china tho, so might be LIES!
hmmm…
This was released today in UroToday, a medical journal type thing. you have to sign up to read it so ill just post it as a quote.. Its not really telling us anything new but im really glad that ketamine related bladder problems are being recognised as a problem and that they are taking the time to investigate further..
Sunday, 30 May 2010
SAN FRANCISCO, CA USA (UroToday.com) May 30, 2010
New research sheds light on recreational drug’s impact on urologic health
Ketamine, a popular recreational drug whose abuse by young people, is associated with smaller bladder capacity, pelvic pain, and voiding frequency and urgency, according to new research presented at the 105th Annual Scientific Meeting of the American Urological Association (AUA). Researchers from Hong Kong will share data on ketamine’s impact on urologic function from a community survey of teenagers with a history of using the drug. The study data will be presented to the media during a special press conference on Sunday, May 30 at 11:30 a.m. PDT.
Researchers surveyed 66 teens and young adults, aged 13 to 25, through a series of clinic sessions. More than 97 percent had a history of ketamine abuse. The team administered a self-assessment survey examining pelvic pain, urgency and frequency, and conducted kidney ultrasound, post-void bladder scans and uroflowmetry studies on the patients. Subjects using ketamine more than five times per week reported detrimental effects on the bl
adder. Patients also self-reported the use of nimetazepam (51 percent), cocaine (45.7 percent) and cannabis (39.4 percent). Patients who had abused ketamine for more than 24 months had increased pelvic pain, urgency and frequency (6.16 vs. 3.92), and those who had used the drug more than five times per week had a markedly decreased bladder capacity (187.7 ml vs. 337 m.) compared to those who had a lower frequency of using the drug. Symptom scores improved in patients who ceased using the drug, and continued to improve over time. Those who had abstained for a full year had improved bladder capacity.
“Recreational drug use is an ongoing problem, not just in the United States, but around the world,” said Tomas L. Griebling, MD, MPH, a spokesman for the AUA. “The good news from this study is that ketamine users can improve their urologic symptoms by quitting.”
Ketamine is an anesthetic (NMDA receptor antagonist) that at high levels can bind to opioid μ receptors and sigma receptors. As a recreational drug, ketamine induces a state of dissociation, similar to the effects produced by phencyclidine (PCP). Ketamine is known to cause amnesia, delirium, impaired motor function, high blood pressure and respiratory problems.
About the American Urological Association: Founded in 1902 and headquartered near Baltimore, Maryland, the American Urological Association is the pre-eminent professional organization for urologists, with more than 16,000 members throughout the world. An educational nonprofit organization, the AUA pursues its mission of fostering the highest standards of urologic care by carrying out a wide variety of programs for members and their patients.
#506
THE ASSOCIATION OF PELVIS PAIN, URGENCY AND FREQUENCY SCORE AND BLADDER CAPACITY WITH STREET KETAMINE ABUSE – OBSERVATIONS FROM A PILOT COMMUNITY SURVEY OF YOUNG DRUG ABUSERS.
Siu-king Mak*, Tsz-yeung Chan, Bo-bik Wu, See-ming Hou, Kam-hung Yip, Chi-yin Man, Hong Kong, Hong Kong
Introduction and Objectives: A multidisciplinary outreach volunteer clinic is set up in community centers to assess the physical, psychological and urological status of teenagers with history of ketamine abuse.
Methods: 66 teenagers aged 13 to 25, were recruited and being assessed in 6 clinic sessions from July to September 2009. Urological assessment included a self-reported-questionnaires on pelvis-painurgency- and-frequency (PUF), uroflowmetry , post void bladder scan and kidney ultrasonography. The amount of ketamine usage was estimated by the weight of table salt using a electronic balance. The ketamine dose per week was calculated as the weight of table salt in gram multiplied by the frequency of ketamine usage per week. Associations were tested using Mann-Whitney U test for numeric nonparametric variables.
Results: Twenty-four percnet are female. First drug abuse was as early as age ten. 77% reported recreation as the main reason of drug abuse. 48.5% claimed no dependency yet. 70% can afford the drug cost while 43% could get drug from friends for free. The commonest drug being abused was ketamine (>97%) followed by nimetazepam (51%), cocaine (45.7%) and Cannabis (39.4%). Ketamine abuse of more than 24 months is observed to have higher PUF symptom score (6.16 vs 3.92; p=0.043) and bordersome score (2.68 vs 1.42; p=0.025).Abuse more than 5 times a week is associated with smaller bladder capacity (187.7ml vs 337.0ml; p=0.025). More that 10gm-salt-equivalent per week is noted with higher symptom (6.2 vs 4.8; p=NS) and bordersome score (2.8 vs 1.0; p=0.009). Longer quitting-duration (1 year, 6 months, 3 months vs <3 months) was associated with lower symptom (5.54, 5.25, 5, 4.11) and bothersome score (2.08, 1.75, 1.67, 0.89). Higher bladder capacity is noted in those quitted for one year (386.7ml vs 243.0ml; p=NS).
Conclusions: This is the first community survey of urological function in teenagers with history of street ketamine abuse. It suggested some detrimental effect of street ketamine abuse. It provides evidence for further longitudinal study and material for cognitive therapy to them. Source of Funding: none
ALSO i found this..
“possible CURE for ketamine side-effects”
Possible cure for ketamine side-effects
^not too sue on this one, but would be great if it turns out to be something that could help
