A drug used in human and veterinary medicine primarily for the induction and maintenance of general anesthesia.Ketamine makes the user feel disassociated from their body and can cause hallucinations. The user may feel sleepy or sluggish, or confused and clumsy. They may babble, appear drunk, or have trouble remembering who they are.Since ketamine is an anesthetic, there is a risk of vomiting associated with use. Eating or drinking before taking the drug increases the risk of choking on one’s own vomit. Ketamine affects the central nervous system, and can reduce the amount of oxygen getting to the brain and other vital organs.
@daceymathers 443662 wrote:
A drug used in human and veterinary medicine primarily for the induction and maintenance of general anesthesia.Ketamine makes the user feel disassociated from their body and can cause hallucinations. The user may feel sleepy or sluggish, or confused and clumsy. They may babble, appear drunk, or have trouble remembering who they are.Since ketamine is an anesthetic, there is a risk of vomiting associated with use. Eating or drinking before taking the drug increases the risk of choking on one’s own vomit. Ketamine affects the central nervous system, and can reduce the amount of oxygen getting to the brain and other vital organs.
never been sick off k and i’ve put 1.5g up my nose before possibly 2g. after about 1g it starts just dripping and is a waste though.
i don’t normally pass on drug scare news, and ok this is not a peer-reviewed result yet but we knew much of this already. it is looking quite serious for health effects of long term k.
“There is growing evidence that chronic use of the recreational drug ketamine is linked with severe bladder problems. The findings may also have implications for the drug’s use as an antidepressant.Used safely as a medical anaesthetic and analgesic for decades, ketamine has also risen in popularity as a recreational drug. The first case of severe bladder problems linked with ketamine use was documented in 2007, but little is known about the extent or cause of the problem.
Now a group of surgeons and scientists have raised the alarm in a review calling for more investigation ( BJU International, DOI: 10.1111/j.1464-410X.2010.10031.x). They highlight effects such as incontinence and bladder shrinkage, as well as damage to the kidneys and ureter in people using ketamine frequently.”It has a major impact on users such that they can be incontinent or have enormous pain,” says Dan Wood, a consultant urologist at University College London Hospitals, who led the review. He has seen 20 chronic ketamine users with urinary problems in the last three years and had to remove four patients’ bladders.
The review suggests that heavy users are more likely to suffer symptoms, and about 20 per cent of people who have taken high doses of ketamine several times a week over months to years have experienced urinary tract problems.
“[Recreational use] is a growing problem in the UK, Australia and New Zealand, and it’s a huge problem in south-east Asia, especially in Hong Kong,” says Val Curran, a psychopharmacologist at University College London, who is leading a review of ketamine for the UK’s Independent Scientific Committee on Drugs.
Previously, it was thought that bladder problems might have been down to substances combined with the drug for street sale. In an as-yet-unpublished study, Simon Baker and Jennifer Southgate at the University of York, UK, added ketamine to human urothelium cells, which line the bladder. With increasing doses, the cells rapidly became cytostatic – they stopped growing – and then died with further increases.
Ketamine has recently shown promise in treating depression. In a study published this week, Lisa Monteggia and colleagues at the University of Texas Southwestern Medical Center in Dallas show that in mouse models of depression, ketamine promotes the rapid synthesis of a protein known to have antidepressant effects, called brain-derived neurotrophic factor (BDNF). They suggest that this may provide a therapeutic target for developing fast-acting antidepressants, especially important for people at risk of suicide (Nature, DOI: 10.1038/nature10130).
“We are excited that ketamine could be the basis for a whole new generation of drugs, but concerned that these might show similar side effects to ketamine,” says Baker. Understanding more about ketamine’s actions could support the development of antidepressants without these negative effects.
(some of the articles linked in are expensive subscription journals, so quoting from the magazine for “fair use” discussion)
use and abuse innit?
I wouldn’t class the NS as one of the right-wing scare rags and TBH its only pulling together the info that has been found by health services worldwide..
what I think is more worrying (and hasn’t yet been noted as much) is it appears that a certain amount of ketamine users are self-medicating to alleviate chronic depression brought on by the combined use of MDMA and other stimulants. Certainly I noticed that amongst my friends in both SE England and East Anglia…
interesting, gl. as you say the self medication aspect of k doesn’t seem to have been looked into yet. but that crossed my mind too when i read recently as to how powerful and immediate k is as an antidepressant (ref. “Secrets of ‘Magic’ Antidepressant Revealed”, Science Daily blog 20/08/2010)
like sinner69 says it’s about use versus abuse, but assuming that harmful effects == abuse, it seems the safe limits are a lot lower than anyone realised. it used to be thought that k was absolutely safe, for instance, because it’s used as an anaesthetic on babies and the elderly. now we’re learning that it’s not, when it comes to long term use.
the research paper by val curran that i linked in has some results on mental abilities after heavy k use, too.
hopefully knowing this stuff can help people keep their konsumption down to a couple of lines per week, for instance (yeah right ;-))
most drug use that is not recreational is self medication, there is sumting about to survive in the a crazy world you better off being a bit crazy your self, if not, self medication is might a decent way out to widstand all the pressure and bullshit you have to go through to live…. anyway we are all on drugs anyway, we drink tea, coffee, eat pills(vitamins etc) smoke, do training to get the endorphine to flow….and eat sugar to be awake and the list goes on and on… all for to alternate your normal state and then innocent substances become drugs in my world…. but that said, all should know that keta has big black abusive side and it have consequences for the individual human in the long run both mentally and physically….
Infact DM Turner labeled ketamine as the heroin in the psychedelic world…he should know he had a massive keta habit that ended with that it took his life in a way, he k-holed in the bath tub and….that was it…
@General Lighting 444488 wrote:
I wouldn’t class the NS as one of the right-wing scare rags and TBH its only pulling together the info that has been found by health services worldwide..
what I think is more worrying (and hasn’t yet been noted as much) is it appears that a certain amount of ketamine users are self-medicating to alleviate chronic depression brought on by the combined use of MDMA and other stimulants. Certainly I noticed that amongst my friends in both SE England and East Anglia…
i started using K after i quit using MDMA. I used to be fully mentally addicted to weekend MDMA+Weed (And whatever else we could throw in the mix) but now MDMA makes me feel disgusted at how that mentally drains you into a depressed wreck unable to eat or sleep. Started using K because for some reason my body doesn’t reject it at all and the powder tastes amazing and there’s no comedown maybe just a lack of motivation and tiredness after, or if you go overboard the stomach, piss pains, cramps etc!!!
But to be honest if you could force 20 grams of most powders inside you abusively over a couple of days i’m sure you’d get the same body effects probably a lot worse.
when i first started using cramps never happened and i could sniff 1.5g lines just for the hell of it and feel basically nothing and was able to do this for quite some time before i properly paid for it. The reason i got the first cramps IMO was because by then i started combining drugs to try and get the buzz back and was taking lots of tramadol which makes k go up the nose completely fine and was sniffing lots and lots of crystal k and not even crushing it up due to laziness and the fact that i felt so invincible to it and it didn’t even hurt.
after the first cramp it started going downhill and then i had about 4-5 in total the last one being the most ill i’ve ever felt in my life, lasted around 5-6 days the full on paralyzing pain then for an extra 7-8 days after my insides and chest hurt chronically and i had major anxiety and depression when waking up. that last cramp was due to some major issues in my life which just pushed me over the edge and made me completely break down into the worst depression because i felt completely and utterly cheated by my 2 best friends and felt like there wasn’t much hope so ended up forcing the remains of my k in me as fast as possible because i wanted rid of it and am too addicted to throw it down the toilet… also i believe i ODed on 5-HTP and vitamins as i double dosed twice as i was so mentally fucked i couldn’t remember if i dosed 5-HTP or not.
now i slowly started slipping back into usage because all my friends sell it and use it non-stop and i just cannot escape it, i can stop doing it but it means i have to pretty much say goodbye to my friends and at my age that’s not really something i want to do but i’m getting support from places and family to try and kick this fucking crap. Before i could barely sniff any k but then i started throwing loads of valium in me which seems to somehow take away any stomach troubles and opiates including the odd bit of heroin which seems to be creeping into my life in a not too nice way.
these days i’ll be boshing 5-6 different drugs at once just to sort out anxiety, pain etc etc and because it makes me invincible and turns me into someone so friendly and care free that i just love to rub off my happiness onto others and say stuff i can’t while sober.
drugs seem to be everywhere now always available and there’s so much peer pressure to be on everyone else’s level, not being on their level is the most boring thing ever just people chatting shit all night.
when i made the p0ly’s sober diary thread i was actually doing very well yet everyone was always hassling me asking me why i’m not getting on the level constantly trying to get me on it with them, went to that royal wedding free party and just cracked then slowly started falling back into a spiral of self destruction (the reason i made that thread, to see how long it’d be before all the abuse came back). Going off to france on friday for 2 and a half weeks to completely detox and get healthy again and getting support from many people trying to help me to stop using so much.
i honestly believe drugs have helped me at this stage to turn me into a much better, less insecure, happier, more funny and interesting person but it’s only a matter of time before i just end up like everyone else i see going down the pan and completely losing it. so many of my friends are completely fucked one of them has taken a 400 pound projector off me and borrowed 100 pound and has now completely ignored all of us and this is the guy who i saved from committing suicide who always said he’d be there for me…. even his girlfriend keeps lending him money which she isn’t getting back and i believe has finally had enough from word of mouth yesterday.
not a nice state of affairs to see and i don’t want to be next in line, thankfully i’ve never pissed blood or had any bladder issues too bad but i know for a fact it will come if i don’t stop.
reason why i am at this point is because it’s like drilled into me just like how you’d greet someone or say goodbye, we just buy drugs instinctively also because i find it hard to put up with people for much time but when using i can listen to people all night long and not get bored and want to go home.
thought i’d just let all this out as am feeling a bit down and thought it might help just to get it all in writing, had the best weekend though… won’t be forgetting it for a long time, should be ok in the morning. just want to get my usage to special occasions only but seems like there’s a special occasion every day being peer pressured into it!! not quite sure what to do at this point but feeling a bit better now.
@p0ly 444515 wrote:
i started using K after i quit using MDMA. I used to be fully mentally addicted to weekend MDMA+Weed (And whatever else we could throw in the mix) but now MDMA makes me feel disgusted at how that mentally drains you into a depressed wreck unable to eat or sleep. Started using K because for some reason my body doesn’t reject it at all and the powder tastes amazing and there’s no comedown maybe just a lack of motivation and tiredness after, or if you go overboard the stomach, piss pains, cramps etc!!!
But to be honest if you could force 20 grams of most powders inside you abusively over a couple of days i’m sure you’d get the same body effects probably a lot worse.
when i first started using cramps never happened and i could sniff 1.5g lines just for the hell of it and feel basically nothing and was able to do this for quite some time before i properly paid for it. The reason i got the first cramps IMO was because by then i started combining drugs to try and get the buzz back and was taking lots of tramadol which makes k go up the nose completely fine and was sniffing lots and lots of crystal k and not even crushing it up due to laziness and the fact that i felt so invincible to it and it didn’t even hurt.
after the first cramp it started going downhill and then i had about 4-5 in total the last one being the most ill i’ve ever felt in my life, lasted around 5-6 days the full on paralyzing pain then for an extra 7-8 days after my insides and chest hurt chronically and i had major anxiety and depression when waking up. that last cramp was due to some major issues in my life which just pushed me over the edge and made me completely break down into the worst depression because i felt completely and utterly cheated by my 2 best friends and felt like there wasn’t much hope so ended up forcing the remains of my k in me as fast as possible because i wanted rid of it and am too addicted to throw it down the toilet… also i believe i ODed on 5-HTP and vitamins as i double dosed twice as i was so mentally fucked i couldn’t remember if i dosed 5-HTP or not.
now i slowly started slipping back into usage because all my friends sell it and use it non-stop and i just cannot escape it, i can stop doing it but it means i have to pretty much say goodbye to my friends and at my age that’s not really something i want to do but i’m getting support from places and family to try and kick this fucking crap. Before i could barely sniff any k but then i started throwing loads of valium in me which seems to somehow take away any stomach troubles and opiates including the odd bit of heroin which seems to be creeping into my life in a not too nice way.
these days i’ll be boshing 5-6 different drugs at once just to sort out anxiety, pain etc etc and because it makes me invincible and turns me into someone so friendly and care free that i just love to rub off my happiness onto others and say stuff i can’t while sober.
drugs seem to be everywhere now always available and there’s so much peer pressure to be on everyone else’s level, not being on their level is the most boring thing ever just people chatting shit all night.
when i made the p0ly’s sober diary thread i was actually doing very well yet everyone was always hassling me asking me why i’m not getting on the level constantly trying to get me on it with them, went to that royal wedding free party and just cracked then slowly started falling back into a spiral of self destruction (the reason i made that thread, to see how long it’d be before all the abuse came back). Going off to france on friday for 2 and a half weeks to completely detox and get healthy again and getting support from many people trying to help me to stop using so much.
i honestly believe drugs have helped me at this stage to turn me into a much better, less insecure, happier, more funny and interesting person but it’s only a matter of time before i just end up like everyone else i see going down the pan and completely losing it. so many of my friends are completely fucked one of them has taken a 400 pound projector off me and borrowed 100 pound and has now completely ignored all of us and this is the guy who i saved from committing suicide who always said he’d be there for me…. even his girlfriend keeps lending him money which she isn’t getting back and i believe has finally had enough from word of mouth yesterday.
not a nice state of affairs to see and i don’t want to be next in line, thankfully i’ve never pissed blood or had any bladder issues too bad but i know for a fact it will come if i don’t stop.
reason why i am at this point is because it’s like drilled into me just like how you’d greet someone or say goodbye, we just buy drugs instinctively also because i find it hard to put up with people for much time but when using i can listen to people all night long and not get bored and want to go home.
thought i’d just let all this out as am feeling a bit down and thought it might help just to get it all in writing, had the best weekend though… won’t be forgetting it for a long time, should be ok in the morning. just want to get my usage to special occasions only but seems like there’s a special occasion every day being peer pressured into it!! not quite sure what to do at this point but feeling a bit better now.
hope you manage to get on top of things mate, perhaps moving away from the area is worth considering?
@extraslim 444538 wrote:
hope you manage to get on top of things mate, perhaps moving away from the area is worth considering?
not really very possible at this current time and i’d rather just sort myself out where i have a lot of friends around. if i left the area i’d probably just get stuff through the post and use it to fill the void of not having no friends etc.
if its any help cramps are caused by the fact that k is really acidic … i drink load of water and also gavisgon helps. ha though ideally no k would probably help the most.
i havent had any for nearly a month (well properly) cos where i live is having a total k drought. its really annoying.Though i guess it is good in many ways.
@mai 444568 wrote:
if its any help cramps are caused by the fact that k is really acidic … i drink load of water and also gavisgon helps. ha though ideally no k would probably help the most.
i havent had any for nearly a month (well properly) cos where i live is having a total k drought. its really annoying.Though i guess it is good in many ways.
i found gulping water down like a maniac til you are burping non stop for 5 mins seems to clean you out and avoid most shit.
@mai 444568 wrote:
if its any help cramps are caused by the fact that k is really acidic
are we sure of this? how do you know?
sounds rather dubious to me
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